What Is Pyometra in Dogs? Protecting From Pyometra

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Author: Jeanette Hampton

What is pyometra in dogs? This simple question opens the door to a crucial discussion about a hazardous condition that all dog owners should be aware of.

What Is Pyometra in Dogs

It is a serious and potentially fatal condition.⚠️ As dog lovers, it is our responsibility to stay equipped with the right knowledge in order to prevent the risk, let’s see how can we do it and keep our dogs happy and healthy.🐶

What Is Pyometra in Dogs?

Pyometra is a severe and potentially life-threatening uterine infection that affects unspayed female dogs, primarily during or after their reproductive years.

The condition arises when the uterine lining undergoes abnormal changes, leading to a pile of pus within the uterus. This build-up of infected material can cause the uterus to become distended and, in some cases, fracture, resulting in severe complications.

Pyometra is a serious condition that demands quick medical attention.🏥 Let’s see some of the causes and risk factors:

Hormonal Factors

Hormonal imbalances play a crucial role in the development of pyometra in dogs. The primary hormonal factor is progesterone, a hormone produced during the second half of the oestrous cycle (the cycle of reproductive readiness).

happy dog in the ground

When progesterone levels remain heightened📈 without pregnancy, it causes changes in the uterine lining, making it more susceptible to infection. This hormonal imbalance creates an environment in which bacteria🦠 can thrive, leading to pyometra.

Breed Predisposition

Certain dog breeds have a higher predisposition to pyometra than others. Breeds that are more prone to the condition include the Rottweiler, Golden Retriever, and German Shepherd, among others.

While pyometra can affect any breed, these dogs may be genetically🧬 more susceptible to hormonal imbalances or anatomical factors that increase their risk.

Age and Reproductive History

Pyometra typically occurs in middle-aged to older unspayed dogs, usually from around 6 years of age and older.⌛ Dogs that have had multiple oestrous cycles and pregnancies without following spaying are at greater risk.

Each oestrous cycle without pregnancy increases the likelihood of hormonal imbalances and the potential for uterine infection. Furthermore, the longer a dog goes without being spayed, the higher the cumulative risk of pyometra becomes.

dog playing with flowers

Estrogen or fake estrogen drugs⚕️ make the effects of progesterone on the uterus stronger.

Sometimes, doctors use medicines with both estrogen and progesterone to treat female reproductive issues, but if a female dog isn’t spayed, we need to keep a close eye on her to stop🚫 pyometra from happening”, confirms Malcolm Weir from WebMD.

Symptoms of Pyometra in Dogs

Recognising the early warning signs and seeking quick veterinary care is crucial in treating pyometra before it moves to these dangerous complications. Here are signs of pyometra in dogs:

Early Warning Signs

Dogs with pyometra often drink more water and urinate frequently due to hormonal imbalances and the body’s response to infection. A pus-like or bloody discharge from the vulva is a common early sign of pyometra. It may be the first noticeable symptom.

Affected dogs may become unusually tired or lack energy.📉 This is often a subtle but important change in behaviour. A decreased or complete loss of appetite is common. Dogs may refuse to eat, even when offered their favourite treats.🍭

What Is Pyometra in Dogs

Advanced Symptoms

As the uterus fills with pus, the abdomen may visibly swell, resembling pregnancy. This is a critical sign that the condition is advancing. Advanced pyometra can lead to gastrointestinal symptoms, including vomiting and diarrhoea.

Dogs may run a fever and become weak due to the systemic effects of the infection. Persistent vomiting, diarrhoea, and increased thirst can lead to dehydration, which further aggravates the dog’s condition.

Let’s understand some of the major complications:

  • Uterine Rupture: One of the most severe complications of pyometra is uterine rupture, where the infected uterus tears. This is a life-threatening emergency.[1]🦺
  • Sepsis: The infection from pyometra can enter the bloodstream, causing sepsis, a severe and potentially fatal condition affecting multiple organs.
  • Kidney and Liver Dysfunction: The infection can affect the kidneys and liver, leading to organ dysfunction and additional health problems.
  • Shock: In severe cases, pyometra can cause shock, characterised by a rapid drop in blood pressure and severe illness, which may be fatal.


The vet will conduct a physical assessment, paying attention to signs like abdominal enlargement, pain on palpation, and any vaginal discharge. They’ll also inquire about the dog’s recent behaviour and symptoms.

visiting vet

Imaging techniques, such as ultrasound, are often used to visualise the uterus and confirm the diagnosis. Additionally, blood tests🩸 are employed to assess the dog’s overall health, detect signs of infection, and evaluate organ function.

These tests may include a complete blood count (CBC) and a biochemical profile. This test 🧪 allows vets to make a conclusive diagnosis and determine the best course of treatment, whether through medical management or surgery.

Treatment Options

Let’s understand the treatment options we have to stop the pyometra in dogs:

Medical Management

Medical management is considered for cases where surgery might pose significant risks, or when the dog’s overall health is too fragile for immediate surgery.

It typically involves antibiotics💊 and prostaglandins, which help to relax the cervix and promote uterine contractions to expel the infected material.

While this treatment can be successful in some cases, it is associated with a higher risk of repetition and may not fully address the underlying hormonal issues that contributed to the condition.

Surgical Intervention

Surgical intervention, often referred to as an ovariohysterectomy or spaying, is the most common and effective treatment for pyometra. It involves the removal of the uterus and ovaries, which not only treats the current infection but also eliminates the risk of future pyometra.

petting dog

This procedure is curative and offers the best chance for the dog’s long-term health. It is usually performed once the dog’s overall condition is stable enough for surgery.

Potential Risks and Benefits

Medical management may spare the dog from surgery, but there is a risk of recurrence and the persistence of hormonal issues. Surgery is a one-time solution that prevents future pyometra but requires anaesthesia and carries the usual surgical risks.⚠️

It’s essential to discuss the options with your vet, taking into consideration your dog’s age, overall health, and the severity of the condition. The chosen treatment should be according to the individual dog’s needs and cases, with a focus on ensuring their health and well-being.

Prevention and Recovery

Ideally, spaying should be performed before the dog’s first oestrous cycle🔁 to significantly reduce the risk. Spaying eliminates the risk of both pyometra and unwanted pregnancies, contributing to a healthier and more comfortable life for your dog[2]. Here are some more prevention tips:

dog playing with flowers
  • Recognize the increased risk in older, unspayed females, especially those with a history of repeated oestrous cycles. Avoid using hormonal medications that can heighten the risk, particularly in intact females.
  • Regular check-ups with your veterinarian are crucial for early detection of any health issues, including pyometra. Routine examinations and discussions with your vet🧑‍⚕️ can help you make informed decisions.
  • After surgical intervention, follow your veterinarian’s post-operative care instructions diligently. Ensure your dog has a quiet, comfortable place to recover, with minimal physical activity during the healing period.
  • Recognize that surgical intervention is curative, eliminating the risk of pyometra.

Focus on maintaining a balanced diet, regular exercise, and weight management to promote overall well-being.❤️‍🩹


❔Can a Dog Survive Pyometra?

It is a very serious condition that affects female dogs and, if left untreated, it can be fatal. Treatment for pyometra includes emergency surgery to remove the uterus, antibiotic medications, and intravenous fluids. The sooner a dog with pyometra is treated, the better her chance of survival and recovery.

❔What Is Pyometra in Dogs?

Pyometra is a serious and potentially life-threatening infection of the uterus that causes it to fill with bacteria and pus. Many dogs with a pyometra have vaginal discharge and may feel very sick with a poor appetite, lethargy, vomiting and sometimes increased thirst or urination.

❔How Do You Detect Pyometra?

If there is discharge from the cervix or a bloated abdomen in an older female dog that has not been spayed, these are indicators that diagnostic tests should be done to confirm whether a dog has pyometra. Diagnostics would include a blood test to look at the white blood cell count and level of globulins in the blood


In conclusion to “What is pyometra in dogs?” Pyometra, a life-threatening uterine infection that primarily affects unspayed female dogs,🐶 serves as a reminder of the essential role we play in our dogs’ lives.

Responsible pet ownership involves making informed decisions about spaying, recognising breed predispositions, and avoiding hormonal medications that may heighten the risk of pyometra.

By providing proper care,❤️‍🩹 choosing the right preventative measures, and staying in close partnership with our vets, we can safeguard our dogs from this difficult condition and ensure their lifelong health and happiness.


  1. Professional, C. C. M. (n.d.-d). Uterine rupture. Cleveland Clinic.
  2. Sharma, P. (2023, January 11). What Is Spaying and Neutering: 5 Ways These Procedures Keep Your Furry Buddy Hale And Hearty. Netmeds.
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Jeanette Hampton
Jeanette Hampton is a content writer at WWD and an expert on all things pets. She’s been writing pet blogs for over 5 years and knows everything there is to know about dogs. Jeanette enjoys writing about pet-related topics because she enjoys helping people learn more about their furry friends.

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